Research & Treatment Update

By Peggy Willocks

New to Virtuality in 2002 will be this regular column on research in Parkinson's Disease. Every day new discoveries are being made involving breakthroughs in treatment and advances leading to a cure. While this column will not be all inclusive, it will give the reader some insight as to some areas of research that might be of interest to the lay reader.

Your assistance would be appreciated in providing linked sites to Virtuality concerning new treatments, medications, Clinical Trials or research findings. Please email such findings to Virtualityez@yahoo.com with RESEARCH as the subject.

This issue will examine an instrument (assessment or test) used often by physicians to measure your abilities or disabilities due to Parkinson's. The instrument is online at the site of a professional organization known as We Move, located at www.wemove.org . The site has information about various movement disorders, including Parkinson's Disease. This assessment tool is most often used in a research project to measure how much or little improvement patients have during the study.

The UPDRS (Unified Parkinson's Disease Rating Scale), is quite long and detailed. As you know, there presently is no specific laboratory test to determine that Parkinson's disease is the definite diagnosis. Physicians base the diagnosis on symptoms (tremor, rigidity, bradykinesia, balance and response to PD medication). Of course, blood tests, MRI of the brain, and other diagnostic tools are used to rule out other diseases or abnormalities.

This link provides the complete URDRS assessment:

http://www.wemove.org/par_rate.html  UPDRS
* Since its introduction in 1987, the UPDRS has been used extensively by researchers and physicians around the world.

If you would be interested in knowing what studies are being conducted or planned in PD research, or if you might be interested in being a participant, bookmark these site:

http://clinicaltrials.gov/

http://www.acurian.com/patient/?camp=mlcthtml

Another procedure that is providing relief for some is the DBS (FDA approved) and the STN (not yet approved). These are defined below:

Deep brain stimulation (DBS) uses an implanted electrode to deliver continuous high-frequency electrical stimulation to either the thalamus, globus pallidus (GPi), or the subthalamic nucleus (STN), another part of the brain controlling movement. High frequency stimulation of cells in these specific areas actually shuts them down, helping to rebalance control messages in the movement control centers in the brain.

We have many readers who have undergone these DBS procedures. For the March issue, Virtuality would like to print your experiences with this procedure. Send a short summary by the end of February, 2002, of your story and DBS to Virtualityez@yahoo.com with DBS story as the subject. Please idicate in the body of your story if permission is granted for readers to contact you and provide that information. Your identity or contact info will not be released without your permission.

Help find a hope and a cure!

 

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